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Titlebook: In Vivo Spectroscopy; Lawrence J. Berliner,Jacques Reuben Book 1992 Springer Science+Business Media New York 1992 cells.magnetic resonance

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NMR Methods in Studies of Brain Ischemia,, 1986; Cohen, 1987). Due to relatively low sensitivity, NMR methods detect only those metabolites whose concentrations are ≥ 1.0 mM and that are not tightly bound to macromolecules or immobile cellular structures. A large number of NMR-observable nuclei have been used as naturally occurring or artificial probes for . studies.
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NMR Methods in Studies of Brain Ischemia,ole animals (Ackerman .., 1980). It has provided an attractive method for continuously monitoring metabolic changes in short time intervals in the physiological and pathophysiological states of an organ or a tissue of an individual animal (Shulman, 1979; Gadian, 1982; James and Margulis, 1984; Radda
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,,H NMR Studies of Cellular Metabolism, relied primarily on the observation of nuclei other than protons. In particular, .P and .C NMR studies of intact systems have provided information about the energetics and biochemistry of intact cells, and applications involving these nuclei have been reviewed extensively (Hollis, 1980; Iles ..,198
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geographical or social region. Calculations are often made, for example, of the incidence and spread of a disease (Friedman, Primer of epidemiology, 1994). Typically these estimations are based on the presence of various empirical referents, particularly certain demographic and environmental factors
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