书目名称 | In Silico Tools for Gene Discovery | 编辑 | Bing Yu,Marcus Hinchcliffe | 视频video | | 概述 | Provides brief introductions and clear instructions for the applications of each particular in silico tool.Features a wide variety of tools with easy to follow methodologies.Includes key tips and vita | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .As functional genomics has become one of the major focuses in molecular biology, the need for more sophisticated tools to assist in the identification of the functionality of undefined genes and the correlation of DNA variants with a particular phenotype has increased greatly. .In Silico Tools for Gene Discovery. collects many common and useful .in silico. tools available today. The volume begins by investigating locus mapping information on linkage analysis, association mapping, integrative analysis, and exome analysis as well as tools for DNA marker selection, .in silico. PCR, and statistical analysis. It continues with a section on gene discovery from a defined locus, including gene prioritization, knowledge tracking, and data mining, and concludes with several useful .in silico. tools presented for the functional characterization of genes, which include DNA sequencing analysis, variant characterization, as well as RNA and protein analysis. Written in the highly successful .Methods in Molecular Biology™. series format, chapters include introductions to their respective topics, step-by-step, readily reproducible protocols, and vital notes on troubleshooting and avoiding kno | 出版日期 | Book 2011 | 关键词 | DNA variants; Functional gene characterization; Functional genomics; Locus mapping; Quantitative PCR; Und | 版次 | 1 | doi | https://doi.org/10.1007/978-1-61779-176-5 | isbn_softcover | 978-1-4939-6188-7 | isbn_ebook | 978-1-61779-176-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2011 |
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