| 书目名称 | Immunotherapy of Hepatocellular Carcinoma | | 编辑 | Tim F. Greten | | 视频video | | | 概述 | Contributions from experts in the field.Provides insights into new therapies.Provide an overview over fundamental immunological questions in liver cancer and tumorimmunology | | 图书封面 |  | | 描述 | .In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. .Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer..Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement a | | 出版日期 | Book 2017 | | 关键词 | Hepatocellular carcinoma; liver cancer; Immunotherapy; tumor immunology; Immune-based treatment | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-64958-0 | | isbn_softcover | 978-3-319-87911-6 | | isbn_ebook | 978-3-319-64958-0 | | copyright | Springer International Publishing AG 2017 |
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发表于 2025-3-21 18:33:51
