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Titlebook: Immunotherapy of Cancer; Mary L. Disis Book 2006 Humana Press 2006 Antigen.T cell.cell.cell therapy.clinical trial.cytokine.cytokines.imag

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书目名称Immunotherapy of Cancer
编辑Mary L. Disis
视频video
概述Includes supplementary material:
丛书名称Cancer Drug Discovery and Development
图书封面Titlebook: Immunotherapy of Cancer;  Mary L. Disis Book 2006 Humana Press 2006 Antigen.T cell.cell.cell therapy.clinical trial.cytokine.cytokines.imag
描述Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practicaltreatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunologic monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.
出版日期Book 2006
关键词Antigen; T cell; cell; cell therapy; clinical trial; cytokine; cytokines; imaging; imaging techniques; immuno
版次1
doihttps://doi.org/10.1385/1597450111
isbn_softcover978-1-61737-645-0
isbn_ebook978-1-59745-011-9Series ISSN 2196-9906 Series E-ISSN 2196-9914
issn_series 2196-9906
copyrightHumana Press 2006
The information of publication is updating

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Tumor-Reactive T-Cells for Adoptive Immunotherapy, spontaneous.” As these trials are not solely conducted for treating cancer patients, but also for research on human beings, the resulting scientific observations have increased our understanding of T-cell activation, homing, and survival, as well as of the possibility of disrupting regulatory mecha
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Tumor-Induced Immune Suppression and Immune Escape,c profile of tumor cells because of their genetic instability. These topics are reviewed in this chapter, following a brief description of the essential components of a TA-specific immune response. Lastly, potential strategies to counteract tumor immune suppression and immune escape mechanisms are d
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Manipulation of Lymphocyte Homeostasis for Enhancing Antitumor Immunity,ive antitumor responses have been unsuccessful to control disease because of inadequate T-cell activation, the fleeting duration of antitumor T-cell responses, and an active suppressor system that downplay immune responses.
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di­ cal school clinical practice situation, I set aside one day each week to puzzle over the theoretical questions that my clinical experience gener­ ates. Often isolating these underlying theoretical questions provides guidance into the most relevant empirical literature. I have found that this wee
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Özlem Türeci MD,Thorsten Klamp PhD,Michael Koslowski MD,Sebastian Kreiter MD,Ugur Sahin MDy in my medi­ cal school clinical practice situation, I set aside one day each week to puzzle over the theoretical questions that my clinical experience gener­ ates. Often isolating these underlying theoretical questions provides guidance into the most relevant empirical literature. I have found that this wee978-1-4757-9708-4978-1-4757-9706-0
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