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Titlebook: Immunotherapy of Cancer; An Innovative Treatm Yoshiyuki Yamaguchi Book 2016 Springer Japan 2016 biomarkers.cancer vaccine.immune checkpoint

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Polysaccharidesgainst several kinds of cancer in Japan. All of them are derived from mushrooms, and about 25 years has passed since their clinical approval. Since their mechanisms of action have become elucidated basically and clinically by many investigators, they are discussed here from an immunological point of
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BCG Its main objectives constitute of treatment of existing or residual cancer, prevention of tumor recurrence, prevention of disease progression, and prolongation of survival. The initial clinical stage and grade of bladder cancer remains the main determinant factors in survival, irrespective of the t
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Natural Killer Cellsitical players in anticancer immunity. However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cells..In this review, I mentioned the role of NK cell receptors, therapeutic NK cells, and NK cell modulation in order to enhance anticancer immunity. Namely, I
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γδ T Cell-Based Cancer Immunotherapy exert potent cytotoxicity against a variety of cancer cells irrespective of MHC class I expression, and bridge innate and adaptive immunity. They comprise 1–5 % of peripheral blood mononuclear cell (PBMC); the majority of them express the Vγ9Vδ2 T cell receptor that recognizes phosphoantigens. Ther
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