Titlebook: Immunotherapy for Pediatric Malignancies; Juliet C. Gray,Aurélien Marabelle Book 2018 Springer International Publishing Switzerland 2018 A

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Immune Biomarkers in Paediatric Malignancies,ents are rarely effective in all patients, predictive biomarkers to identify those most likely to benefit from a specific therapy are useful. Identification of biomarkers may also improve our understanding of how treatments work, as well as resistance mechanisms, and thus be used not only to anticip

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Future Perspectives,tment of many tumour types, and changing the paradigm of treatment in oncology by targeting immune cells rather than cancer cells. Antagonistic antibodies blocking immunosuppressive pathways such as PD-1/PD-L1 have shown anti-tumor activity in patients with advanced relapsed and refractory cancers t