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Titlebook: Immunology: Overview and Laboratory Manual; Tobili Y. Sam-Yellowe Textbook 2021 Springer Nature Switzerland AG 2021 immunity.immune system

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Apoptosissis and organ development. Cytotoxic T cells and NK cells induce apoptosis in target altered host cells. Apoptosis also known as programmed cell death or cellular suicide is a process of cell death that involves a defined death pathway as a result of extrinsic and intrinsic signals effective in the
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Antigens . that is recognized by host immune cells to be “different” or foreign to host tissue. The agent may be natural or synthetic or it may be altered host molecules unrecognizable to host immune cells as self. Collectively, the term used for pathogens, foreign macromolecules or altered host molecules i
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Immunoglobulin and T Cell Receptor Gene Rearrangements marrow for B cells and in the thymus for T cells. The genes encoding the B cell receptor and T cell receptor undergo rearrangements and recombination with the aid of lineage specific recombinases which together with DNA repair enzymes facilitate the recombination of the variable genes of heavy and
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Cytokinesitic cells, B and T lymphocytes. Cell signaling due to ligation of cytokines with their receptors results in cell growth, differentiation and cell migration. Cytokines are small proteins secreted by cells in the body. Most are secreted by leukocytes and have a variety of functions in the immune syst
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Complement Fixation generated by a number of serine proteases among the components. The end result of the enzyme cascade in three different pathways, is the insertion of a membrane attack complex in cell membranes that results in the lysis of target cells. The initiation components of the three pathways of complement
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