Titlebook: Immunology of the Skin; Basic and Clinical S Kenji Kabashima Book 2016 Springer Japan KK 2016 Skin immunology.Barrier functions.Allergies.S

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Lymphatic Vesselsd transport of immune cells to regional lymph nodes. Pathological impairment of lymphatic vessel function increases the risk of infection and of the development of certain types of tumors. New lymphatic vessel growth called lymphangiogenesis occurs during embryonic development and in pathologic sett

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Hair Folliclesas an object of developmental and stem cell research, however, little attention has been paid to HF in the light of immunology. Previous observations supported that HF might enjoy immune privilege by suppressing immune-related antigen expression and producing immunosuppressive molecules, indicating

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Adipose Tissueshe innate immune system are activated in the absence of external pathogens, leading to pathologic consequences. Recent studies have revealed that obesity is associated with significant increases of M1 macrophages in adipose tissues that produce pro-inflammatory cytokines such as TNF-α and IL-1β. In

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Innate Immunityed molecular patterns (PAMPs). In addition, danger-associated molecular pattern (DAMPs) molecules also initiate a noninfectious inflammatory response through the innate immune system. Many nonimmune cells resident in the skin, as well as immune cells, are endowed with an array of pattern recognition

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C-Type Lectin Receptorsund proteins. Among them, those expressed on phagocytes and working as pathogen pattern-recognition receptors were designated as C-type lectin receptors (CLRs), in accordance with Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-I–like receptors (RLRs). Most of the genes for CLRs are c

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managed, but it can also pose severe risks to human health. The quality of the land, water and air may be threatened by improper animal waste handling. Animal manure can be adequately handled using a variety of approaches, ranging from simple, low-cost procedures to complex strategies. Microorganis

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Kenji Kabashima M.D., Ph.D.e to regulate its environmental matters, e.g., regarding land, water, territorial sea, or airspace. However, not all activities carried out on territorial grounds remain there. Some activities, especially the kind producing fumes or gases, may have strong effects on areas beyond national jurisdictio

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