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Titlebook: Immunology of the Neonate; G. Roberto Burgio,Lars Åke Hanson,Alberto G. Ugazi Conference proceedings 1987 Springer-Verlag Berlin Heidelber

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Complement Function in the Neonate,e complexes, and opsonize microorganisms. Activation of the complement cascade may occur via the antibody-dependent classical pathway (C1, C2, and C4) or the antibody-independent alternative pathway (factor B and factor D) (Arnaout 1985; Pangburn 1983; Reid 1981). Activation of early acting componen
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Modulation of Nonspecific Defense Mechanisms in the Neonate,o activation of the inflammatory process. In addition, a variety of defense patterns can be elicited, i.e., multifactorial immaturity of several components; latent activation of some activities; episodes of sudden, frequently uncontrolled functional hyperactivity; and exhaustion or deactivation of v
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T-Cell Development and Function: Relationship to Immunodeficiencies,process, promise to be of considerable help in the understanding of several human immunodeficiency disorders. The earlier steps of intrathymic differentiation have recently been shown to involve the expression of surface molecules, such as the receptors for interleukin-2 (IL-2) and the T11 determina
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Activation and Functional Capacity of Neonatal T Cells: Analysis of Interleukin-2 and Interleukin-2ocytes which express T-lineage cell surface molecules during the 9th to 10th weeks, and these cells become responsive to activating stimuli during the 10th to 12th weeks of gestation. Such T lymphocytes are found in the spleen 3-4 weeks after their appearance in the thymus and subsequently enter the
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T and NK Lymphocyte Subpopulations in the Neonate,acting and often conflicting factors. The fetal immune system must cope with potentially aggressive maternal cells as well as invading pathogens but at the same time must avoid the risks of the potentially almost as catastrophic effects of a strong reaction against maternal antigens. Obviously, the
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Immunity and Infections in the Neonate,on types of neonatal bacterial infection - sepsis and meningitis - ranges from 3 to 6/1000 live births in the United States. Approximately 20%-50% of infected infants die of the illness, and for those who are treated successfully for meningeal infection, neurological sequelae are found in about one-
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