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Titlebook: Immunology of Rheumatic Diseases; Sudhir Gupta,Norman Talal Book 1985 Plenum Publishing Corporation 1985 autoimmunity.diseases.molecular b

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书目名称Immunology of Rheumatic Diseases
编辑Sudhir Gupta,Norman Talal
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图书封面Titlebook: Immunology of Rheumatic Diseases;  Sudhir Gupta,Norman Talal Book 1985 Plenum Publishing Corporation 1985 autoimmunity.diseases.molecular b
描述Recent developments in basic science and clinical rheumatology make it appropriate at this time to create a volume devoted to the immunology of rheumatic diseases. The impact of molecular biology, gene cloning, and new technologies for establishing hybridomas and T-cell lines in the laboratory is now beginning to be felt in clinical medicine. There is a general air of excitement and a feeling that we stand on the threshold of a new era in molecular medicine and clinical science. It is this excitement that we have tried to capture in this book. This volume is divided into five sections entitled Basic Mechanisms, Autoimmunity, Classical Concepts of Rheumatic Diseases, Pathogenetic Mechanisms, and Therapy. This is not an arbitrary arrangement but represents our belief that from an understanding of basic mechanisms of disease pathogenesis will come new and more successful forms of treatment for the sufferers of rheumatic disorders. We have tried in the selection of authors to choose internationally recognized experts who have both a scientific and a clinical orientation to their subjects. We believe the marriage of clinical and basic disciplines represents the best hope for rapid knowl
出版日期Book 1985
关键词autoimmunity; diseases; molecular biology; pathogenesis; rheumatic diseases
版次1
doihttps://doi.org/10.1007/978-1-4613-2493-5
isbn_softcover978-1-4612-9509-9
isbn_ebook978-1-4613-2493-5
copyrightPlenum Publishing Corporation 1985
The information of publication is updating

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Lymphocyte Subpopulationsnctions of various subsets of cells of T- and B-cell lineages. The heterogeneity of T-cell subsets in humans was first defined by the presence of distinct receptors for immunoglobulin isotypes and more recently by the presence of differentiation antigens as defined by monoclonal antibodies. This has
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The Autologous Mixed Lymphocyte ReactionAt midcentury, Burnet (1959) proposed his immunologic theory of clonal selection, which included deletion of autoreactive clones during ontogeny. According to this theory, autoantibodies and other autoimmune reactions are the result of the appearance of forbidden clones secondary to somatic mutation
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