Titlebook: Immunology of Pregnancy; Gil Mor Book 20061st edition Springer-Verlag New York 2006 T cell.apoptosis.complications.cytokine.embryo.fetus.h

deviate

Potential Role of Glucocorticoids in the Pathophysiology of Intrauterine Growth Restriction (IUGR),t” to poor utero-placental perfusion due to defective trophoblast invasion that ultimately compromises fetal well-being..–. The resultant hypoxia curtails the remodeling of uterine vessels by invasive cytotrophoblasts in the second trimester..,. Our results suggest that mediators of fetal stress [i.

gregarious

NK Cells and Pregnancy,rived trophoblasts can have a profound impact on pregnancy. Altered NK cell numbers and activity have been associated with a variety of clinical conditions such as endometriosis, recurrent pregnancy loss, and preeclampsia. Uterine NK cells have a unique phenotype compared to blood NK cells and this

怒目而视

shrill

Indoleamine 2,3 Dioxygenase-Dependent T Cell Suppression and Pregnancy,l immune system protects both mother and fetus from invading pathogens during gestation, but also has to maintain immunological tolerance towards the fetus. Medawar proposed three ways in which this paradox might be resolved: physical segregation of maternal and fetal tissues, immunologic immaturity

等级的上升

Characterization of Human Dendritic Cells at the Materno-Fetal Interface,ises as to how the maternal immune system handles the foreign fetal antigens leading to that tolerance. Focussing on the various subsets of immunocompetent cells playing in concert with the human immune system, tolerance induction nowadays is often accredited to a newcomer, at present the “hottest s

试验

MHC Molecules of the Preimplantation Embryo and Trophoblast,the paradox of maternal tolerance was first raised by Peter Medawar. Preimplantation embryos express paternal antigens early in development. After implantation, placental tissue is derived from both maternal tissue and paternal-antigen expressing fetal tissue that is in intimate association with and

ambivalence

ornithology

草本植物

The Role of Regulatory T Cells in Materno-Fetal Tolerance,s despite exposure of the maternal immune system to potentially immunogenic fetal tissue. Local immune evasion mechanisms are thought to prevent maternal immune aggression towards the fetus. Nevertheless, maternal lymphocytes capable of mediating anti-fetal immune aggression are detectable throughou

cumber

The Eutherian Fetoembryonic Defense System Hypothesis: An Update,ydrate sequences that coat the murine zona pellucida are also upregulated on activated lymphocytes, and some participate in gamete binding. This overlap indicates that there may be a “species recognition system” (SRS) that is employed to identify both immune cells and gametes in the context of “spec