Titlebook: Immunology of Human Papillomaviruses; Margaret A. Stanley Book 1994 Plenum Press, New York 1994 Antigen.antigen presentation.cancer.cell.d

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V. Vonka,E. Hamsiková,J. Novák,V. Hofmannová,N. Munoz,S. de Sanjosé,K. Shah,Z. Roth

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Detection of HPV-16 E2 Protein in Cervical Keratinocytes there are now several. reports. of the existence of episomal. HPV-16 DNA capable of encoding full length E2 protein in late stage tumours. In addition, a recent HPV-16 isolate defective for keratinocyte immortalisation was shown to contain a mutation in the E2 gene; cotransfecting a wild type E2 re

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Humoral Immune Response to Genital Human Papillomavirus Infectionsquantities has been impossible. With the advances of recombinant DNA technology the genomic clones of all different HPV types became available and expression of individual. genes can be achived in a variety of prokaryotic and eukaryotic systems such as E.coli, yeast, Baculovirus and Vaccinia. A desc

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Prevalence of Antibodies Against Defined HPV Epitopes Among Incident Cases of Cervical Neoplasia: Cu. Furthermore, there exist no theoretical. grounds to assume that conformational. epitopes would be more specific than linear epitopes. On the contrary, conformational. epitopes are, by definition, more sensitive to conformational. change and assays based on such epitopes are therefore likely to hav

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e past decade leaves little doubt that infection with certain HPV types (the so called "oncogenic HPV‘s" 16, 18 and their relatives) is the major risk factor in the development of cancer of the uterine cervix in women. Since an infectious agent, a virus, is implicated as the main aetiologic factor in this dis978-1-4613-6041-4978-1-4615-2449-6

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Eileen Epsaro,Jarrett Burton,Sheila Mathieson,Joseph Merola,Jeffrey A. Sandsg design decisions. This result means that engineers must be on their guard with respect to under-design or over-design of systems with and without the threat of climate change, but that the sequential nature of the decision-making does not call for drastic action in the early time periods. Key Word

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