Titlebook: Immunology and Aging; Takashi Makinodan,Edmond Yunis Book 1977 Plenum Publishing Corporation 1977 autoimmune disease.diseases.immune syste

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The Pathogenic Role of Age-Related Immune Dysfunctions,rst because any discussion on aging and immunity should be based on the prevailing immunological theories and models. The age-related immune dysfunctions will then be surveyed and the need for in depth analysis will be emphasized. Finally, an outline of agerelated pathology, which could be a consequ

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Suppressor Cells in Aging,m is not unique in showing declining function with age. What strikes some people as paradoxical is that this decline is often accompanied by an increase in autoantibody production. However, with the general recognition in the past few years that there are subsets of T cells which act to suppress the

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Immunological Responsiveness and Aging Phenomena in Germfree Mice,ular, it is possible to eliminate one important variable, i.e., infection, in studies designed to define the relationship between the immune response and aging. Such infection may be overt or occult. Of perhaps greater importance, in the context of this discussion, is the fact that germfree animals