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Titlebook: Immunological Approaches to the Diagnosis and Therapy of Breast Cancer; Roberto L. Ceriani Book 1987 Plenum Press, New York 1987 breast ca

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书目名称Immunological Approaches to the Diagnosis and Therapy of Breast Cancer
编辑Roberto L. Ceriani
视频video
图书封面Titlebook: Immunological Approaches to the Diagnosis and Therapy of Breast Cancer;  Roberto L. Ceriani Book 1987 Plenum Press, New York 1987 breast ca
描述Once again we have gathered to discover and evaluate advances made in our ability to understand. diagnose and possibly treat breast cancer with the new reagents provided by monoclonal antibody techniques. In the last two years since our first International Workshop on Monoclonal Antibodies and Breast Cancer there has been an enormous surge in the number and quality of applications for these new reagents. Solid achievements have been made in identification and quantitation of estrogen and progesterone receptors. in histopathological diagnostic procedures. in serum diagnosis. and we are witnessing now the first attempts to treat breast cancer with immunoconjugates. Cytosolic estrogen receptors can now be quantitated with monoclonal antibodies. and also their cellular distribution can be directly assessed histologically. In addition. monoclonal antibodies to progesterone receptors have been generated that show promise in having similar uses as those to the estrogen receptor. In the field of diagnosis. the use of monoclonal antibodies has permitted the development of serological approaches for early diagnosis by identifying and measuring breast epithelial antigens in serum. and of hist
出版日期Book 1987
关键词breast cancer; cancer; cancer treatment; clinical trial; tumor
版次1
doihttps://doi.org/10.1007/978-1-4613-1903-0
isbn_softcover978-1-4612-9059-9
isbn_ebook978-1-4613-1903-0
copyrightPlenum Press, New York 1987
The information of publication is updating

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Immunological Approaches to the Diagnosis and Therapy of Breast Cancer
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Immunological Approaches to the Diagnosis and Therapy of Breast Cancer978-1-4613-1903-0
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Monoclonal Antibody Studies of Drug Resistancey is correlated with the elevated expression of a plasma membrane glycoprotein with a molecular weight of 170,000 daltons, termed P-glycoprotein or P170.. Recently, a 600-base pair (bp) complementary DNA (cDNA) encoding part of the P-glycoprotein was obtained from aλ gt 11 expression vector library
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Detection and Assay of the 52K Estrogen-Regulated Protease in Mammary Tumorswth and invasion of breast cancer cells. We have focused on one of these proteins of 52,000 daltons (52K) which is induced specifically by estrogens and secreted by the MCF7 and ZR75-1 human breast cancer cell lines (5). We first summarize our knowledge of the structure and function of this protein
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Diversity of Antigenic Expression on Normal and Malignant Human Mammary Cells Recognized by a New Paeas 126G5 binds to the cytoplasm of luminal epithelium..The monoclonals showed a range of positive reactions from 30 to 100 percent in about 30-35 breast cancer cases tested. Seven monoclonals proved to be strongly reactive in a high percentage of malignant cases. All of them had a significant bindi
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