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Titlebook: Immunological Approaches to Contraception and Promotion of Fertility; G. P. Talwar Book 1986 Springer Science+Business Media New York 1986

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Lack of Toxicological Effects Following Seven Years of Active Immunization of Rhesus Monkeys with tregular menstrual cycles. The mechanism(s) of antifertility action involves inpaired luteal function and/or failure of chorionic gonadotropin to stimulate the corpus luteum. Because of the significant cross reaction of the oLHβ-antibodies with serum LH and a moderate increase in circulating immune c
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Improved Immunogenic Formulations for Antigonadotropin Response,81, 1984) and rats (Hulme et al., 1980). A vaccine consisting of beta subunit of hCG conjugated with tetanus toxoid (TT) was proposed earlier (Talwar et al., 1974, 1976). This vaccine induced antibodies to both hCG and TT and thus provided additional immunoprophylactic benefit against tetanus. After
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Enhancement of Antibody Response to an Antigonadotropin Vaccine by use of Adjuvants,d adsorbed on Al (OH). resulted in low and short-lived antibody titers in some of the women studied (1,2). It was therefore judged necessary to find ways to enhance the antibody response. Approaches explored included the use of other adjuvants to supplement the aluminum hydroxide and the use of modi
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Cloning and Expression of Biologically Active Human Fertility Hormones,a major role in ovulation, spermatogenesis and conception. hCG is secreted by the developing placenta during the first trimester of pregnancy. Both hLH and hFSH are secreted by the pituitary and together play a central role in regulating menstrual cycle and ovulation.
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Cloning and Expression of Lutropin Genes,licle-stimulating hormone (follitropin, FSH) and thyroid-stimulating hormone (TSH) is produced and secreted by the anterior pituitary gland and CG by the placenta. LH and FSH, the pituitary gonadotropins, stimulate the production of the sex steroid hormones and gametogenesis. As such, they are impor
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Immunization Against FSH as a Method of Male Contraception,for Applied Research on Fertility Regulation (PARFR), Northwestern University. PARFR invited Professor Eberhard Nieschlag of the Max Planck Clinical Research Unit for Reproductive Medicine, Munster, Federal Republic of Germany, to present a paper on immunization against FSH as a male method of ferti
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