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Titlebook: Immunodeficient Animals for Cancer Research; Stephen Sparrow Book 1980 The Medical Research Council 1980 amyotrophic lateral sclerosis (AL

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楼主: Ingrown-Toenail
发表于 2025-4-1 04:35:34 | 显示全部楼层
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A prospective test for human tumour rejection antigens?, normal immunological mechanism while the nude mouse cannot reject an allograft of normal tissue. Prehn and Outzen (1977) have demonstrated that allogeneic and animal tumours grow better in nude mice if the animals are X-irradiated. It is probable that X-irradiation would also facilitate the growth of human tumours in nude mice.
发表于 2025-4-1 12:22:37 | 显示全部楼层
Cytofluorometric analysis of tumours in nude mice,killer cell activity (Holden .., 1978), site of tumour (Auerbach .., 1978), and inoculum size (Helson .., 1977) in the animal host may influence heterotransplanted tumour growth. Information concerning the growth patterns of untreated heterotransplanted tumours is thus required for a better understanding of how we can use this model.
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Comparison of the growth of xenografts in various kinds of immunodeficient mice,subcutaneously in nude and B mice than do carcinomas of the breast and prostate or lymphomas or leukaemias. Certainly, our attempts to grow human breast carcinomas in certain immune-suppressed mice and hamsters, or immune-privileged sites, have usually proved unsuccessful (Detre .., 1975).
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