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Titlebook: Immunoconjugate Therapy of Hematologic Malignancies; Steven T. Rosen,Timothy M. Kuzel Book 1993 Springer Science+Business Media New York 1

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n hydrodynamics will require four assumptions in addition to the assumption that a small element of the fluid obeys Newton’s second law. Except for Sects. 4.5 and 4.6 this chapter will be concerned with the simplest cases, in which the . particles can be considered one at a time, each one obeying Ne
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New approaches to radiolabeling monoclonal antibodies,njected dose per gram, localizes in tumor following intravenous injection [.]. The low tumor uptake in patients may be related to such factors as antibody dilution following injection [.], the slow rate of diffusion or penetration of antibody molecules across the vascular endothelium [.], and restricted blood flow in tumor tissue [.].
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Immunotoxins for the therapy of graft versus host disease,ransplant therapy to those without such a donor through the use of bone marrow from mismatched related or matched unrelated donors. Once moderate to severe GVHD occurs, up to half of patients will die despite therapeutic intervention.
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Radioimmunotherapy of lymphoma,, mention new obstacles to successful incorporation of radiolabeled MoAbs into standard oncologic therapy, and suggest future directions that may lead to enhanced effectiveness of radioimmunoconjugates.
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Imaging and dosimetry determinations using radiolabeled antibodies, technology [.], the development of radiolabeled anti-tumor monoclonal antibodies (MoAb) as imaging and therapeutic reagents promises to add an element of specificity not previously available with conventional techniques.
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