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Titlebook: Immunobiology of Proteins and Peptides · I; M. Z. Atassi,A. B. Stavitsky Book 1978 The Editor(s) (if applicable) and The Author(s), under

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书目名称Immunobiology of Proteins and Peptides · I
编辑M. Z. Atassi,A. B. Stavitsky
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Immunobiology of Proteins and Peptides · I;  M. Z. Atassi,A. B. Stavitsky Book 1978 The Editor(s) (if applicable) and The Author(s), under
描述One of the central questions in immunology is the understanding in molecular terms of antigen-antibody interactions and of the cellu­ lar recognition of antigens. It is hoped that this understanding will extend eventually to the immunobiological basis of host defense to infectious agents and of tissue damage or deranged cell functions which stem from these reactions. A variety of natural and artificial substances have been used as models for these studies. Emphasis was placed upon substances of known and relatively uncomplicated chemical structures. These included polysaccharides, amino acid polymers, nu­ cleic acids and haptens. On the other hand. until recently there has been very little information on protein antigens. The complexity of these molecules posed an immense chemical obstacle to precise immuno­ chemical analysis. Indeed, it is this difficulty with proteins that spurred the synthesis and immunological studies of amino acid poly­ mers. The control and normal regulation of the immune system at the cellular-molecular interface and the great majority of antigens asso­ ciated with immune disorders are attributed to protein molecules. In the last few years great advances hav
出版日期Book 1978
关键词antibody; antigen; immune system; immunobiology; immunology; proteins
版次1
doihttps://doi.org/10.1007/978-1-4615-8858-0
isbn_softcover978-1-4615-8860-3
isbn_ebook978-1-4615-8858-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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Immunobiologic Properties of the Major Antigenic Determinants of the Ferredoxin Molecule not demonstrate any obvious similarities. However, sequences identified as determinants in a number of proteins frequently constituted terminal sequences or sterically prominent regions of the molecule. In this laboratory, an in-depth study of the major antigenic regions of the ferredoxin molecule from .. was undertaken.
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First Consequences of the Determination of the Entire Antigenic Structure of Sperm-Whale Myoglobin and the successful extrapolation of the antigenic structure of sperm-whale Mb to human hemoglobin strongly demonstrated that the antigenicity of certain parts of a protein molecule is primarily dependent on the uniqueness of their conformational locations.
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Recognition of Lysozyme by Lymphocyte Subsetsmical modification have so far proven unsuccessful. In a second line of experimentation the response to CM-lysozyme of mice which are genetically unresponsive to native lysozyme was assessed and found deficient. The implications of these findings are discussed.
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perience despite geographical distance and cultural difference. The book is structured around themes such as work, culture, diasporas, gender and sexuality, and race..978-3-030-45903-1978-3-030-45901-7
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perience despite geographical distance and cultural difference. The book is structured around themes such as work, culture, diasporas, gender and sexuality, and race..978-3-030-45903-1978-3-030-45901-7
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