Titlebook: Immunobiology of Proteins and Peptides VI; Human Immunodeficien M. Zouhair Atassi Book 1991 The Editor(s) (if applicable) and The Author(s)

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Maternal Antibody Epitope Mapping in Mother-to-Child Transmission of HIV,threatens to grow in the coming years.. increasing numbers of women of childbearing age become HIV infected through intravenous drug abuse or heterosexual transmission.. The seroprevalence in an unselected population of childbearing women has for instance been reported to be as high as 2% in an inne

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Common Sequence in HIV-1 GP41 and HLA Class II Beta Chains can Generate Crossreactive Autoantibodieand the amino-terminal of the beta chain of all human HLA class II antigens (aa 19–25). Murine monoclonal antibodies raised against synthetic peptides from these homologous regions bound not only to the isolated peptides, but also to “native” HLA class II molecules on cells. Screening of sera from H

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conservative

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Mhc-Molecule

Activation of Prodrugs by Antibody-Enzyme Conjugates,lls. Promising results, both . and ., have been obtained in studies involving immunoconjugates such as MAb-toxins (Vitetta et al., 1987; Blakey et al., 1988), MAb-drugs (Pietersz, 1990; Koppel, 1990), and radiolabeled MAbs (Goldenberg, 1990). Based on these findings, many such conjugates are current

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Cancer Imaging and Therapy with Radiolabeled Antibodies,eutic measures, and to provide leads to understanding mechanisms of cancer development, progression, and, ultimately, prevention. Enzymes, hormones, receptors, oncogene products, and other cancer-related molecules, including the extensive family of tumor-associated and oncofetal antigens, have been

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