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Titlebook: Immunobiology of Organ Transplantation; David S. Wilkes (Calvin H. English Professor of Me Book 2004 Springer Science+Business Media New Y

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书目名称Immunobiology of Organ Transplantation
编辑David S. Wilkes (Calvin H. English Professor of Me
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图书封面Titlebook: Immunobiology of Organ Transplantation;  David S. Wilkes (Calvin H. English Professor of Me Book 2004 Springer Science+Business Media New Y
描述Currently, individuals interested in seeking an in-depth discussion of transplantation immunology must seek individual articles published in several journals, or extrapolate information from various non-transplant immunology textbooks. The purpose of this text is to provide the reader with a single source of information for the basic science of immunobiology of organ transplantation. It is unique that it focuses on immunobiology from the basic research side, with an emphasis on the cellular and molecular levels. .The readers will be physicians, scientists, and graduate students interested and engaged in the study of immunology as it relates to allo- and xenotransplantation. This book is designed to be the reference standard for the immunobiology of transplantation.
出版日期Book 2004
关键词Antigen; Chemokine; atherosclerosis; cell biology; cytokine; genetics; histocompatibility; immunobiology; in
版次1
doihttps://doi.org/10.1007/978-1-4419-8999-4
isbn_softcover978-1-4613-4754-5
isbn_ebook978-1-4419-8999-4
copyrightSpringer Science+Business Media New York 2004
The information of publication is updating

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Immunity of Allograft Rejection: An Overviewlmost universally does, lead to complete destruction of the transplanted organ over time. This chapter offers an overview of the features and mechanisms of the immune system that work in concert to interact with and reject the organ allograft. Subsequent chapters will describe the role of distinct c
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MHC: Structure and Function; and continues to form a basis not only for the identification of new molecules that regulate the immune response but also for inciting basic scientists to explore the molecular details of cellular interactions.
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Genetics of CD1 Moleculesobulin.. A cluster of five.genes were identified and designated.and.These five genes are physically very close to one another and likely arose by gene duplication, as the percent homology amongst the various.genes is approximately 80% in the a3 domain, for example. In spite of this, the.genes are su
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Mechanisms of Allorecognition cells interact with determinants presented by allogeneic MHC molecules displayed on donor cells. This phenomenon is dictated by the migration of donor “passenger leukocytes” out of the graft to the host’s lymphoid tissues. Alternatively, in indirect allorecognition, donor antigens are processed by
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Complement System in Allorecognition and Rejection of Organ Transplantsransplants. This type of rejection was named hyperacute to denote that these transplants were rejected within minutes to hours after the surgeon allowed blood to flow into the grafted kidneys. Immunohistological studies demonstrated antibodies and complement components were deposited in the transpla
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