Titlebook: Immune-Mediated Myopathies and Neuropathies; Current Trends and F Balan Louis Gaspar Book 2023 The Editor(s) (if applicable) and The Author

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Classification of Immune-Mediated Myopathiesgenous yet highly specific spectrum of muscular and extra-muscular involvement. Historically, IIM are classified into three major subgroups including polymyositis, dermatomyositis, and inclusion body myositis (IBM) mainly by their clinical or pathological features or both in combination [1–10]. The

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Specific Forms of Immune-Mediated Necrotizing Myopathiesubentities needed to be differentiated [1]. Of note, and although necrotizing myopathies have been described since, the mid-1970s Peter and Bohan did not include them as a separate entity in their dichotomic differentiation between dermatomyositis and polymyositis, which was based on the presence of

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Overlap Myositisectable [1]. In particular, the overlap myositides include idiopathic inflammatory myositis (IIM) with extramuscular symptoms, peculiar systemic lupus erythematosus (SLE), systemic sclerosis (SSc) or Sjögren’s syndrome, frequently associated with specific autoantibodies [2]. The so-called myositis-a

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AntiAMA-M2 Myopathy. Among them, cases of inflammatory myopathy associated with serum autoantibodies exhibit characteristic clinical features by the type of autoantibody [1]. Due to the close association between autoantibodies and characteristic clinical features, these autoantibodies are thought to be important not o

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Mimics of Immune-Mediated Myopathyssociated with other autoimmune diseases. These disorders are characterized clinically by subacute onset of generalized, symmetric proximal muscle weakness. If distal weakness occurs, it is usually a late feature and seldom as severe as proximal weakness. Although dysphagia may occur, especially in

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Current Concepts and Future Prospects in Immune-Mediated Myopathiesd therapies [1]. Therapeutic efforts and successes have sharpened the focus on different molecular aspects of myositides or idiopathic inflammatory myopathies. The once classical classification into dermatomyositis, polymyositis, and inclusion body myositis as the major forms has now been refined by