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Titlebook: Immune Responses to Biosurfaces; Mechanisms and Thera John D. Lambris,Kristina N. Ekdahl,Bo Nilsson Conference proceedings 2015 The Editor(

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书目名称Immune Responses to Biosurfaces
副标题Mechanisms and Thera
编辑John D. Lambris,Kristina N. Ekdahl,Bo Nilsson
视频videohttp://file.papertrans.cn/463/462063/462063.mp4
概述Proceedings of the September 2014 Aegean Conference on Immune Responses to Bio surfaces.Discusses the immune response to biomaterial devices, implants and therapies that can adversely affect clinical
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Immune Responses to Biosurfaces; Mechanisms and Thera John D. Lambris,Kristina N. Ekdahl,Bo Nilsson Conference proceedings 2015 The Editor(
描述​The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.
出版日期Conference proceedings 2015
关键词biomaterials; biomedical implant; cell surface; cell therapy; immune response; organ transplantation
版次1
doihttps://doi.org/10.1007/978-3-319-18603-0
isbn_softcover978-3-319-37277-8
isbn_ebook978-3-319-18603-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approachesal bone support. These mechanistic studies have additionally identified potential therapeutic targets. In this regard, interventional studies in preclinical models have provided proof-of-concept for using complement inhibitors for the treatment of human periodontitis.
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Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplamit IBMIR by administering inhibitors in circulation, by coating the islet surface with inhibitors or by generating transgenic donor animals; these approaches could result in improved xenograft survival.
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Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapyhich can interact with lipid bilayer membranes, without increasing cell volume. Molecules attached to these polymers can protect transplanted cells and islets from attack by the host immune system. We expect that this surface modification technique will improve graft survival in clinical islet transplantation.
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Conference proceedings 2015 who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical
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