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Titlebook: Imago Cosmi; The Vision of the Co Daniele L. R. Marini Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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Daniele L. R. Marinith and rupture. Bench experiments have revealed that as cholesterol undergoes phase transition from a liquid to a solid crystalline it rapidly expands to occupy a greater volume. When this process occurs within the core of an atherosclerotic plaque the rapid volume expansion can lead to disruption o
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Daniele L. R. Marini chapter is to summarize the systemic manifestations of atherosclerosis that result from the release of atherosclerotic debris including cholesterol crystals into the circulation due to spontaneous plaque rupture or iatrogenic injury of the plaque cap..Spontaneous rupture and direct trauma of athero
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Daniele L. R. Marini chapter is to summarize the systemic manifestations of atherosclerosis that result from the release of atherosclerotic debris including cholesterol crystals into the circulation due to spontaneous plaque rupture or iatrogenic injury of the plaque cap..Spontaneous rupture and direct trauma of athero
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Daniele L. R. Marinirogression as well as plaque erosion and rupture that leads to acute atherothrombotic events..The initial evidence suggesting that CCs develop within the plaque core in vivo came from post-mortem and post-surgical specimens that examined the appearance of culprit and non-culprit lesions in animal mo
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Daniele L. R. Marinidence that the pathologic process that leads to valvular degeneration is similar to the atherosclerotic process..Thus, as cholesterol accumulates in the leaflets of native and prosthetic heart valves it predisposes to the formation of cholesterol crystals that trigger an iterative cycle of traumatic
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