| 书目名称 | Imaging in Drug Discovery and Early Clinical Trials |
| 编辑 | Paul L. Herrling,Alex Matter (Director),Markus Rud |
| 视频video | |
| 概述 | Presents new essential technologies.Critical evaluation of new biomarkers.Regulatory issues and potential pitfalls are discussed |
| 丛书名称 | Progress in Drug Research |
| 图书封面 |  |
| 描述 | .In this monograph the contribution of imaging modalities to the various stages of drug discovery and development, from early target validation to their use in clinical development programs, is described. Chapters are devoted to the description of the drug discovery process as such, to the various imaging modalities being used both preclinically and clinically, to applications of imaging during the optimization of a lead compound (addressing issues such as bioavailability and efficacy) and during the drug safety evaluation. A chapter describes imaging biomarkers, their development, advantages and the potential pitfalls associated with their use. In the translation of imaging tools from animals to man regulatory issues have to be addressed, which are dealt with in a separate section. ..The monograph provides a comprehensive overview on the role of imaging in drug discovery today and discusses major developments and trends both with regard to technologies and applications.. |
| 出版日期 | Book 2005 |
| 关键词 | Drug Discovery; Imaging; Trend; fluorescence; lead; optimization |
| 版次 | 1 |
| doi | https://doi.org/10.1007/3-7643-7426-8 |
| isbn_ebook | 978-3-7643-7426-6Series ISSN 0071-786X Series E-ISSN 2297-4555 |
| issn_series | 0071-786X |
| copyright | Birkhäuser Basel 2005 |
发表于 2025-3-21 16:10:18
