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Titlebook: IgG4-Related Sclerosing Cholangitis; Terumi Kamisawa,Myung-Hwan Kim Book 2019 Springer Science+Business Media Singapore 2019 IgG4.Primary

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楼主: clannish
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Imaging: US and CT,ls, storiform fibrosis, obliterative phlebitis, and mild to moderate eosinophilia [1]. IgG4-related sclerosing cholangitis (IgG4-SC) is a biliary lesion associated with IgG4-RD, which is frequently seen in elderly men, characterized by obstructive jaundice owing to a bile duct stricture and responds
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Imaging: EUS and IDUS, often associated with type 1 AIP. Bile duct wall thickening is considered the EUS finding of IgG4-SC with type 1 AIP. Cholangiocarcinoma (CCA) and primary sclerosing cholangitis (PSC) are important diagnoses that should be differentiated from IgG4-SC. IDUS findings of non-stricture bile duct lesion
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Tissue Acquisition for Histologic Diagnosis,extensive fibrosis in the bile duct wall. Histopathologic examination is always necessary for the definite diagnosis of IgG4-SC if there are no other organ involvements such as type 1 AIP, IgG4-related sialadenits or retroperitoneal fibrosis. Endobiliary biopsy by ERC is a standard technique for tis
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Other Organ Involvements,st proposed as a systemic disease in 2003 by Kamisawa et al. following the recognition that a high percentage of patients with autoimmune pancreatitis (AIP) had extrapancreatic manifestations that shared similar histopathological features consisting of dense infiltration of IgG4-positive plasma cell
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Treatment: Immunomodulatory Drugs, cholangiopathy [1]. IgG4-related SC, a distinctive type of cholangitis of unknown etiology, is characterized by increased serum levels of IgG4 and massive infiltration of IgG4-positive plasma cells with extensive fibrosis in the wall of the bile duct. Its cholangiographic features are similar to th
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