书目名称 | Identification of Ligand Binding Site and Protein-Protein Interaction Area |
编辑 | Irena Roterman-Konieczna |
视频video | http://file.papertrans.cn/461/460837/460837.mp4 |
概述 | Comparative analysis of models based on geometry versus those based on knowledge of the biological phenomenon Application note Relation to biological phenomena.All illustrations in full color.A review |
丛书名称 | Focus on Structural Biology |
图书封面 |  |
描述 | This volume presents a review of the latest numerical techniques used to identify ligand binding and protein complexation sites. It should be noted that there are many other theoretical studies devoted to predicting the activity of specific proteins and that useful protein data can be found in numerous databases. The aim of advanced computational techniques is to identify the active sites in specific proteins and moreover to suggest a generalized mechanism by which such protein-ligand (or protein-protein) interactions can be effected. Developing such tools is not an easy task – it requires extensive expertise in the area of molecular biology as well as a firm grasp of numerical modeling methods. Thus, it is often viewed as a prime candidate for interdisciplinary research. |
出版日期 | Book 2013 |
关键词 | bioinformatics; ligand binding; protein-protein complexation; structure of proteins |
版次 | 1 |
doi | https://doi.org/10.1007/978-94-007-5285-6 |
isbn_softcover | 978-94-017-8284-5 |
isbn_ebook | 978-94-007-5285-6Series ISSN 1571-4853 Series E-ISSN 2542-9566 |
issn_series | 1571-4853 |
copyright | Springer Science+Business Media Dordrecht 2013 |