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Titlebook: Ich glaube, es hackt!; Ein Blick auf die ir Tobias Schrödel Book 20143rd edition Springer Fachmedien Wiesbaden 2014 Datenschutz.Hacking.Hac

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Tobias Schrödelenergy supplies, ATP depletion, failure of Ca. buffering systems, excess glutamate release and activation of glutamate receptors. In addition, a reduction in antioxidant enzymes and consequently an increase in free radicals has also been associated with aging. Each of the preceeding alterations woul
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Tobias Schrödelcide gene therapies, gene suppression, or oncolytic viral and non-viral therapies. In this chapter, we will review the historical context of gene therapy and cellular engineering development for the treatment of hematological malignancies and, particularly, in the setting of hematopoietic cell trans
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Tobias Schrödelogenic disorders (Gardner et al., Blood 129:3322–3331, 2017) (refer to subsequent disease-specific chapters in the book). In this chapter, we will highlight the most recent and clinically relevant developments in the arena of gene-modified T-cell-based therapies and hematopoietic stem cellular gene
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Tobias Schrödelnormal and fully functional NK cells that are less inhibited by patient tumor. Despite these encouraging findings, NK cell therapy is limited by the lack of antigen specificity and by tumor escape likely resulting from the formation of a complex network of suppressive components in the tumor microen
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Tobias Schrödeln their own class I MHC molecules to autologous T cells regardless of the MHC alleles expressed by the antigen source. When compared with other APCs, like macrophages, DCs are much more efficient and can elicit responses from very low numbers of T cells. In this chapter we review such and other mech
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Tobias Schrödelcide gene therapies, gene suppression, or oncolytic viral and non-viral therapies. In this chapter, we will review the historical context of gene therapy and cellular engineering development for the treatment of hematological malignancies and, particularly, in the setting of hematopoietic cell trans
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