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Titlebook: International Union of Pharmacology; Proceedings Volume 1 William Paton,James Mitchell,Paul Turner Conference proceedings 1984 Macmillan Pu

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Axonal transport of receptorso membranes, function, inactivation, turnover, and degradation. Because of the dramatic successes in the past ten to fifteen years in identifying receptors, many of the other aspects can be studied. A main interest of our laboratory over the past several years has been the axonal transport of drug and neurotransmitter receptors.
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Exploration of active sites of ,-peptidases necessity dictated by the countermoves — tolerance, intrinsic resistance and, above all, β-lactamase production — made by the bacteria to control our most effective armoury of modern antibacterial chemotherapy. Resistance to β-lactams is a progressive process which is occurring before our eyes, and the need for new antibiotics remains urgent.
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Localization of functional activity in the central nervous system by metabolic probesstanding how the nervous system functions requires knowledge not only of the mechanisms of excitation and inhibition but even more so of their precise localization in the nervous system and the relationships of neural subunits to specific functions.
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Mechanisms of β-lactamase action enough depth) into ‘serine’ enzymes and ‘metal’ enzymes. A second division splits the ‘serine’ enzymes into two classes (called class A and class C), based on their amino acid sequences (Ambler, 1980; Jaurin & Grundström, 1981).
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