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Titlebook: Hypoxia; From Genes to the Be Robert C. Roach,Peter D. Wagner,Peter H. Hackett Book 2001 The Editor(s) (if applicable) and The Author(s), u

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Erythropoietin use and abuseass by recombinant human erythropoietin is associated with a reduction in plasma volume and in some patients, hypertension is induced. Elevation of the red cell mass is also associated with a reduction in cerebral blood flow. When used to gradually elevate the hematocrit to 36% in anemic patients, r
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Mountaineering in thin airrming, which has caused the Khumbu glacier to shrink and slow in recent decades. (2) Risk of death during descent from an 8000-m peak increases with the height of the peak. (3) Risk of death during descent from the summit of Everest or of K2 is elevated for climbers not using supplemental oxygen. (4
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Weight loss at high altitudelanocortin (POMC), orexin A and B (hypocretins), melanin-concentrating hormone (MCH) and ghrelin (endogenous ligand of the growth hormone secretagogue receptor). This overview will introduce the current concepts of the molecular control of energy homeostasis and attempt to reexamine the effects of a
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The heme oxygenase system and cellular defense mechanisms Supra induction of HO-1 completely protects ischemic kidney against tissue pathology. This involves rapid inactivation of the pro-oxidant heme of denatured hemoproteins and converting it to bilirubin and CO. In the case of severe tissue injury, such as compression injury, HO-1 is induced and coloca
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John T. Reeves, MDs 12. International Symposium, John T. (Jack) Reeves, MD, was selected to receive this honor. No one is more deserving, and I say this having had the privilege of Jack’s friendship for nearly half a century.
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Genetic lessons from high altitude Millions of individuals are as hypoxic from congenital or acquired heart or lung disease as healthy individuals may be at altitude. Certain adjustments enable many of such patients to lead nearly normal lives. I will compare their adjustments to those seen in the acclimatization of healthy persons
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