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Titlebook: Hypothermia and Cerebral Ischemia; Mechanisms and Clini Carolina M. Maier,Gary K. Steinberg Book 2004 Springer Science+Business Media New Y

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https://doi.org/10.1007/978-3-658-33991-3 of laboratories throughout the world (for review, . Dietrich, 1996 . and Gordon, 2001 .). Using TBI models of diffuse as well as focal injury, mild and moderate hypothermia have been reported to protect, both histopathologically and functionally. In contrast, posttraumatic hyperthermia worsens trau
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https://doi.org/10.1007/978-3-662-45837-2 hypothermia. In fact, cell counting procedures and infarct volume measurements are often the only endpoint used following global and focal cerebral ischemia, respectively. Furthermore, investigators commonly used short survival times (e.g., 1 d for focal ischemia, 7 d for global ischemia), as these
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https://doi.org/10.1007/978-94-6300-067-3l injury and death when used in conjunction with cardiopulmonary bypass for cardiac surgery or during craniotomies requiring circulatory arrest and a bloodless field. It is a very effective method of obtaining neuroprotection, but carries some risks, including cardiac arrhythmias, clotting defects,
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https://doi.org/10.1007/978-3-319-07410-8 the last two decades that clinical studies have demonstrated that therapeutic moderate hypothermia for brief durations can improve patient outcomes following brain injury. The historical background, recent clinical experience, and mechanisms of action of moderate hypothermia are reviewed.
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Hypothermia,first 6 h after stroke onset in three admission-temperature groups: hypothermic (<36.5°C), normothermic (>36.5–37.5°C), and hyperthermic (>37.5°C). By multiple regression analysis they found body temperature on admission to be highly correlated with clinical outcome and infarct size. The relationshi
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https://doi.org/10.1007/978-3-319-07410-8 the last two decades that clinical studies have demonstrated that therapeutic moderate hypothermia for brief durations can improve patient outcomes following brain injury. The historical background, recent clinical experience, and mechanisms of action of moderate hypothermia are reviewed.
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