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Titlebook: Hypolipidemic Agents; David Kritchevsky Book 1975 Springer-Verlag Berlin · Heidelberg 1975 Arterienverkalkung.Cholesterin.Gallensäure.Hype

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书目名称Hypolipidemic Agents
编辑David Kritchevsky
视频videohttp://file.papertrans.cn/431/430776/430776.mp4
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Hypolipidemic Agents;  David Kritchevsky Book 1975 Springer-Verlag Berlin · Heidelberg 1975 Arterienverkalkung.Cholesterin.Gallensäure.Hype
描述The major cause of death in the Western world is some form of vascular disease; and principal among these forms is atherosclerotic heart disease (ASHD). Although much is known about the etiology and treatment of ASHD, there is, as yet, no specific means of prognosis of an impending coronary episode. There are, however, several indications of susceptibility to coronary disease, generally known as risk factors, the foremost of which is hyperlipidemia. Hyperlipidemia is more commonly designated as hypercholesteremia or triglyceridemia, depending upon which moiety is elevated, but since lipids are transported in the blood as members of a lipoprotein complex, the most descriptive general term would be hyperlipoproteinemia. This volume represents an effort to elucidate the origins and metabolic behavior of lipoproteins and their components, to describe aspects of the morphology, biochemistry and experimental induction of ASHD, and to describe modalities of treatment. The contributions to this book include descriptions of cholesterol synthesis and metabolism, as well as the metabolism of bile acids, the principal products of cholesterol metabolism. There are also chapters on the mechanism
出版日期Book 1975
关键词Arterienverkalkung; Cholesterin; Gallensäure; Hyperlipoproteinämie; Lipoprotein; agents; biochemistry; chem
版次1
doihttps://doi.org/10.1007/978-3-642-66190-7
isbn_softcover978-3-642-66192-1
isbn_ebook978-3-642-66190-7Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin · Heidelberg 1975
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Bile Acid Metabolism,ation of the micellar phase, resulting in lipid malabsorption. Within the intestinal mucosa the bile acids seem to promote esterification of cholesterol and fatty acids and to inhibit cholesterol synthesis.
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https://doi.org/10.1007/978-3-322-95250-9 the differences in the spectra of plasma lipoproteins. Attempts to decrease plasma cholesterol by diet or drugs are based on the hope that reduction in the rate of deposition of cholesterol may retard the development of lesions and also the risk of myocardial infarction.
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Lipoproteins and Lipoprotein Metabolism,cal conditions, the human plasma lipoprotein system may contain more than 500 g of lipids. The aim of the present review is to define the various lipoproteins, describe their routes of metabolism and identify the possible mechanisms by which drugs may affect lipoprotein metabolism.
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The Rationale for Hypolipemic Therapy,l in the risk of heart attack and stroke? The best that can be done is to put together the evidence from all the trials that have been completed, include a factor based on data from animal experimentation, and arrive at a not very well educated guess.
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