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Titlebook: Hypocretins; Integrators of Physi Luis Lecea,J. Gregor Sutcliffe Book 2005 Springer-Verlag US 2005 Hypocretins.Integrators.Physiological.an

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发表于 2025-3-21 16:19:25 | 显示全部楼层 |阅读模式
书目名称Hypocretins
副标题Integrators of Physi
编辑Luis Lecea,J. Gregor Sutcliffe
视频video
概述Represents an interdisciplinary approach to hypocretins that reviews the role of these neuropeptides in neurological disease.Includes supplementary material:
图书封面Titlebook: Hypocretins; Integrators of Physi Luis Lecea,J. Gregor Sutcliffe Book 2005 Springer-Verlag US 2005 Hypocretins.Integrators.Physiological.an
描述The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to observe a full-blown cataplexy attack, it is both dramatic and unnerving. Usually the observer assumes that the loss of muscle tone represents syncope or seizure. In order to educate health professionals and the general public, Christian Guilleminault and I made movies of full-blown cataplectic episodes (not an easy task). We showed these movies of cataplexy attacks to a number of professional audiences, and were eventually rewarded with the report of a similar abrupt loss of muscle tone in a dog. We w
出版日期Book 2005
关键词Hypocretins; Integrators; Physiological; anatomy; brain; hormone; metabolism; neurons
版次1
doihttps://doi.org/10.1007/b107412
isbn_softcover978-1-4614-9806-3
isbn_ebook978-0-387-25446-3
copyrightSpringer-Verlag US 2005
The information of publication is updating

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发表于 2025-3-21 23:30:14 | 显示全部楼层
The Canine Model of Narcolepsylishment of the animal model of narcolepsy was a long and steady effort (especially maintaining the colony and cloning of the gene), which finally lead to the first major breakthrough in over 100 years’ history of narcolepsy research.
发表于 2025-3-22 01:45:18 | 显示全部楼层
Book 2005 sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression.
发表于 2025-3-22 05:02:05 | 显示全部楼层
The Anatomy of Hypocretin Neurons unique afferent and efferent connectivity predicts that this system will further emerge as critical component of a broadening array of brain functions most of which provide necessary support for higher brain functions.
发表于 2025-3-22 10:53:44 | 显示全部楼层
Effects Of Hypocretin/Orexin on the Thalamocortical Activating System different populations of hypocretin neurons, further understanding of what governs hypocretin release in these two areas will yield greater insight into thalamocortical involvement in arousal and attention.
发表于 2025-3-22 14:03:54 | 显示全部楼层
https://doi.org/10.1007/978-3-662-42941-9 animals for systematic studies. Detailed analyses of mouse and rat models of narcolepsy described here would not only deepen our understanding of disturbances of sleep regulation in narcolepsy but might also find out novel aspects of physiological abnormalities in human narcolepsy patients.
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发表于 2025-3-22 22:31:00 | 显示全部楼层
mentary material: The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by
发表于 2025-3-23 03:16:42 | 显示全部楼层
https://doi.org/10.1007/978-3-662-10913-7 unique afferent and efferent connectivity predicts that this system will further emerge as critical component of a broadening array of brain functions most of which provide necessary support for higher brain functions.
发表于 2025-3-23 08:37:31 | 显示全部楼层
https://doi.org/10.1007/978-3-642-99321-3 different populations of hypocretin neurons, further understanding of what governs hypocretin release in these two areas will yield greater insight into thalamocortical involvement in arousal and attention.
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