| 书目名称 | Hydrogen Sulfide in Kidney Diseases | | 副标题 | A Novel Pharmacother | | 编辑 | George J. Dugbartey,Alp Sener | | 视频video | | | 概述 | Covers the latest experimental evidence of hydrogen sulfide for cisplatin-induced acute kidney injury.Provides updates on hydrogen sulfide as a novel pharmacotherapy for chronic kidney disease.Present | | 图书封面 |  | | 描述 | .This is the first book to present the beneficial effects of hydrogen sulfide in the treatment of various kidney pathologies. Hydrogen sulfide (H2S), a gas with a distinctive smell of rotten eggs, was known for over three centuries for its toxicity and death at high concentrations especially among agricultural and industrial workers. This is due to its ability to reversibly antagonize complex IV of the mitochondrial electron transport chain. However, studies over the past two decades have shown that H2S has risen above its historic notorious label and has received significant experimental attention as an endogenously produced gaseous signaling molecule that plays an important role in cellular homeostasis and influences a myriad of physiological and pathological processes at low concentrations. Its production is enzymatically regulated and has specific molecular targets. Several recent .in vitro. and .in vivo. studies have demonstrated that at low micromolar concentrations, H2S exhibits important therapeutic characteristics that target multiple molecular pathways and thereby preventing the development and progression of several pathologies..This beneficial effect of H2S suggests tha | | 出版日期 | Book 2023 | | 关键词 | Hydrogen sulfide; Kidney diseases; Acute kidney injury; Diabetic and hypertensive nephropathy; Chronic k | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-44041-0 | | isbn_softcover | 978-3-031-44043-4 | | isbn_ebook | 978-3-031-44041-0 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 17:23:28
