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Titlebook: Hydro Saline Metabolism; Epidemiology, Geneti Massimiliano Caprio,Fabio Luiz Fernandes-Rosa Reference work 2023 Springer Nature Switzerland

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Mineralocorticoid Receptor and Aldosterone: From Hydro-saline Metabolism to Metabolic Diseases,phron. In the last 10 years, a number of preclinical studies has shown that MR is expressed also in extra-renal tissues such as heart, adipose tissue and vasculature, providing strong evidence that dysregulated extra-renal MR activation contributes to the development of hypertension, obesity, insuli
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Physiology of Vasopressin Secretion,erts its multiple effects by binding to its receptors, classified in different subtypes depending on tissue expression, function, and second messengers. Disorders in AVP synthesis or action can lead to clinical syndromes characterized by water and electrolyte imbalance.
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Familial Hyperkalemic Hypertension (FHHt),t in vitro and in vivo studies have demonstrated that NCC is stimulated by a signaling pathway activated by WNK1 and WNK4, which are themselves targeted for proteosomal degradation by the Cul3-KLHL3 complex..Therefore, the study of this very rare and easily treatable syndrome has led to the discover
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