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Titlebook: Hybrid Systems Biology; Fourth International Alessandro Abate,David Šafránek Conference proceedings 2015 Springer International Publishing

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Integrating Time-Series Data in Large-Scale Discrete Cell-Based Modelsd translating biological motifs from the Pathway Interaction Database to the PH formalism. Then, we propose a way of estimating temporal and stochastic parameters from time-series expression data of action on the PH. Simulations emphasize the interest of synchronizing concurrent events.
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High-Performance Discrete Bifurcation Analysis for Piecewise-Affine Dynamical Systemson analysis that employs coloured model checking to analyse phase portraits bifurcation in rectangular abstractions of piecewise-affine systems. The algorithm works on clusters of workstations and multi-core computers to allow scalability. We demonstrate the method on a repressilator genetic regulatory network.
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