书目名称 | Human iPS Cells in Disease Modelling | 编辑 | Keiichi Fukuda | 视频video | | 概述 | how human disease models are established by patient-derived iPS Cells.a wide range of human diseases such as cardiomyopathy, laminopathy, and Alzheimer’s.Is writtenby top scientists in the field of iP | 图书封面 |  | 描述 | Human iPS cells have a great potential to be cell sources forregenerative medicine because of the promise of infinite self-renewal and thecapability to differentiate into multiple cell types. This book focuses onanother great potential of human iPS cells, which is the establishment of humandisease models using patient-specific iPS cells. Human iPS cells can be easilyobtained from a patient’s somatic cells and provide the entire information on thepatient’s genome. Accordingly, we can generate disease models for inheritablediseases in cell culture dishes using iPS cells. This is a quite new techniquebut holds tremendous potential for our increased understanding of pathogenesis,and will then be the basis for novel drug development industries. All theauthors are leading researchers in this field and they have reported many kindsof patient-derived iPS cells. In this book, they introduce the aspects thatcould be recapitulated in terms of disease modelling as well as furtherinnovative findings such as novel pathogenetic insights and novel therapies. | 出版日期 | Book 2016 | 关键词 | cell reprogramming; iPS cell; iPSCs; induced pluripotent stem cells; stem cel biology; ES cell; disease mo | 版次 | 1 | doi | https://doi.org/10.1007/978-4-431-55966-5 | isbn_softcover | 978-4-431-56739-4 | isbn_ebook | 978-4-431-55966-5 | copyright | Springer Japan 2016 |
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