Titlebook: Human T-Cell Leukemia Virus; Peter K. Vogt Book 1985 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-

Hippocampus

978-3-642-70115-3The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE

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Human T-Cell Leukemia Virus978-3-642-70113-9Series ISSN 0070-217X Series E-ISSN 2196-9965

追逐

Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/h/image/429543.jpg

Virtues

Book 1985patients contain the HTL V provirus but usually do not express it. However, once established in culture, these cells produce viral proteins and release type C particles. Likewise, T cells infected and transformed by HTL V in vitro synthesize virus. Such producing cell lines have been widely used in

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invade

Human T-Cell Leukemia/Lymphoma Viruses: Clinical and Epidemiologic Features, leukemia/lymphoma, the description of which will be a major focus of this review (. et al. 1982; . et al. 1983a; . et al. 1983c). HTLV-II has more recently been isolated, and its relationship to human disease is unclear, although isolates have been obtained from a single patient with T hairy cell l

摊位

The Epidemiology of Human T-Cell Leukemia/Lymphoma Virus,d characterization of the first human type C retrovirus from cultures of cells derived from individuals with T-cell malignancies, leukemias, and lymphomas consisting of mature lymphatic cells (. et al. 1980b).

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上下连贯

A Retrovirus Associated with a Human Leukemia, Adult T-Cell Leukemia,gory called adult T-cell leukemia/lymphoma (ATLL) (.’etal. 1982). However, the abbreviation “ATL”, not 7“ATLL”, will be used in this review for the sake of simplicity, unless otherwise stated. In 1980, over 100 cases of ATL were evaluated in a nationwide survey on T- and B-cell malignancies carried

configuration

Biology of T-Cell Leukemia Virus: Search for an Animal System,ell lymphoma (. et al. 1980, 1981). ATLV was shown to be identical or closely related to HTLV by serology and nucleic acid homology (. et al. 1982). ATLV is now considered an isolate of HTLV (. et al. 1984). Antibodies to HTLV core proteins were also detected in sera of Japanese patients with ATL (.