Titlebook: Human Population Genomics; Introduction to Esse Kirk E. Lohmueller,Rasmus Nielsen Textbook 2021 The Editor(s) (if applicable) and The Autho

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Identity by Descent in the Mapping of Genetic Traitsmilarities in their DNA at genetic marker loci. Conversely, data on the marker genotypes of individuals provides inferences of shared descent of genome in current individuals, not just genome-wide but in specific genome regions. Regions where shared genome accords with phenotypic similarities for a

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What HaveWe Learned fromGWAS?number of genetic markers across the entire genome are tested for association with complex phenotypes in large, unrelated cohorts. This approach has led to hundreds of bona fide and reproducible associations between genotype and phenotype in human populations, with additional studies poised to drama

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Natural Selection, Genetic Variation, and Human Diversitye that have been influenced by natural selection. In this chapter, we discuss methods and models that have been used to better understand how selection has impacted human variation and review studies of natural selection in humans and the stories they reveal about human history.

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