Titlebook: Human Oocytes and Their Chromosomes; An Atlas Berta-Margareta Uebele-Kallhardt Book 1978 Springer-Verlag Berlin Heidelberg 1978 Chromosomes

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Introduction,h the nucleus and the cytoplasm undergo a number of changes. The highly specialized meiotic process causes an exchange of genetic material between pairs of chromosomes and provides the mature oocyte with half the number of chromosomes characteristic of the somatic cells.

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Materials and Methods,The present study of the . has covered a period of several years, from 1971 to 1975. The ovaries were obtained from spontaneous or therapeutic abortions of human fetuses aged from 18 to 27 weeks.

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Terminology,nivalents, bivalents, trivalents, and quadrivalents, respectively. The numerals are followed in parentheses by the chromosomes involved in a rearrangement. Thus, M I, 22, IV (4; 18) indicates a primary oocyte at first metaphase with 22 elements including the XX bivalent and a quadrivalent, consisting of the chromosomes 4 and 18.

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Book 1978ty of diseases was rec­ ognized as due to numerical chromosome anomalies. There followed the discovery that spontaneous abortions are the result of chromosome errors, and specific band patterns of chromosomes allowed identification of minute lesions. The techniques of cell hybridization now allow sp

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