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Titlebook: Human Interphase Chromosomes; Biomedical Aspects Ivan Iourov,Svetlana Vorsanova,Yuri Yurov Book 2020Latest edition Springer Nature Switzerl

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发表于 2025-3-21 18:14:08 | 显示全部楼层 |阅读模式
书目名称Human Interphase Chromosomes
副标题Biomedical Aspects
编辑Ivan Iourov,Svetlana Vorsanova,Yuri Yurov
视频video
概述This is the first title to review modern achievements in the field of the post-genomic era’s genomics of interphase nuclei.The book will provide unique attention to available postgenomic technologies
图书封面Titlebook: Human Interphase Chromosomes; Biomedical Aspects Ivan Iourov,Svetlana Vorsanova,Yuri Yurov Book 2020Latest edition Springer Nature Switzerl
描述.This second edition focuses on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and behavior of the human genome in interphase nuclei at chromosomal level has been repeatedly shown to play a significant role in almost all basic biological processes involved in the processing and inheritance of genetic information within and between species. Accordingly, post-genomic bioscience appeals to basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease. Additionally, elucidating the role of interphase chromosome behavior during development, chromosome/DNA replication, DNA reparation opens new horizons for basic and applied bioscience.. .Studies of interphase nuclei have an appreciable impact on different areas of biomedical sciences such as cell biology, neurobiology, cancer research, developmental biology, epigenetics, cytogenetics, and medical genetics, as a whole. Moreover, development of innovative and emergent technologies to analyze interphase nuclei are closely associated with application of these techniques in diagnostic and research
出版日期Book 2020Latest edition
关键词cytogenetics; developmental biology; genetics; human genome; nuclear organization; cell cycle; cell biolog
版次2
doihttps://doi.org/10.1007/978-3-030-62532-0
isbn_softcover978-3-030-62534-4
isbn_ebook978-3-030-62532-0
copyrightSpringer Nature Switzerland AG 2020
The information of publication is updating

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Eukaryotic Genome in Three Dimensions,f research performed using the proximity ligation protocol. It has been demonstrated that genome folding is much less regular than was previously assumed. On the other hand, the genome was found partitioned into semi-independent structural-functional units commonly referred to as topologically assoc
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Interphase Chromosomes of the Human Brain,mosomal rearrangements). Chromosomal mosaicism and instability rates vary during ontogeny in the human brain: dramatic increase of the rates in the early brain development follows by a significant decrease in the postnatal period. It is highly likely that rates of mosaicism and instability increase
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Senescence and the Genome,e arrest, and although being metabolically active, they exhibit distinct senescence phenotypes. Though cellular senescence may be beneficial in tumour suppression and wound healing, it is commonly associated with age-related diseases. There are various mechanisms and drivers that contribute to agein
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Twenty-First Century FISH: Focus on Interphase Chromosomes,. Generally, interphase fluorescence in situ hybridization (I-FISH) is a basic technological platform for visualization of individual chromosomes (chromosomal regions) in single cells. The achievements of studying human interphase chromosomes have allowed numerous discoveries in chromosome research
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Chromosome-Centric Look at the Genome, required attention to chromosomes is often observed. As a result, chromosome research gradually loses the genetic (genomic) context. Certainly, brilliant insights into chromosome biology obtained by studies dedicated to molecular/cell biology, evolution, biochemistry, biophysics, etc., are fascinat
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ries as¬sist in the telling and retelling of important events. Reflecting on these events allow the ‘processing’, ‘figuring out’ and ‘inquiring’, leading to behavioural actions to change situations. The fact that we are women unites us as we have common elements with our roles both within academia,
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