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Titlebook: Human Insulin; Clinical Pharmacolog D. R. Owens Book 1986 MTP Press Limited 1986 Diabetes.Diabetes mellitus.Pancreas.hormone.insulin

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发表于 2025-3-21 19:22:27 | 显示全部楼层 |阅读模式
书目名称Human Insulin
副标题Clinical Pharmacolog
编辑D. R. Owens
视频video
图书封面Titlebook: Human Insulin; Clinical Pharmacolog D. R. Owens Book 1986 MTP Press Limited 1986 Diabetes.Diabetes mellitus.Pancreas.hormone.insulin
描述Since insulin became available for the treatment of diabetes in 1922 a number of major advances have been made, which include the modification of insulin to vary its timing of action, its purification, and latterly, the production of human insulin. Human insulin in quantities sufficiently large for therapy has been made available by two techniques developed in parallel during the late 1970s. These involve either (i) formulation in E. coli bacteria suitably encoded by DNA recombinant methods of the A- and B-chains of human insulin followed by a chain combination reaction (‘biosynthetic‘ human insulin) or (ii) enzymatic conversion (transpeptidation) of porcine insulin brought to react with a threonine ester by porcine trypsin in a mixture of water and organic solvents, yielding human insulin (‘semi-synthetic‘ human insulin). This book includes the first clinical-pharmacological studies of each of the highly purified ‘semi-synthetic‘ human insulin preparations: Actrapid ® HM; Monotard® HM; Protaphane® HM; Actraphane® HM; and Ultratard® HM (Novo Industri A/S, Copenhagen). The preliminary studies established their safety and efficacy relative to their porcine and bovine counterparts emp
出版日期Book 1986
关键词Diabetes; Diabetes mellitus; Pancreas; hormone; insulin
版次1
doihttps://doi.org/10.1007/978-94-009-4161-8
isbn_softcover978-94-010-8347-8
isbn_ebook978-94-009-4161-8
copyrightMTP Press Limited 1986
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D. R. Owens M.D.owerful tools to represent such networks. One such latent variable network model is a Mixed Membership Stochastic Blockmodel (MMSB), which can discover overlapping communities in a network and has high predictive power. Previous inference methods estimate the latent variables and unknown parameters
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D. R. Owens M.D., clinicians, and teachers. Without ambition we would not be able to confront the problems of young people in an effective way. In this decade, we can see an abundance of problems of young people: football hooliganism, school drop out, vandalism, delinquency, lack ofsocial skills, aggression, and de
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D. R. Owens M.D.levant to treating chronically ill young people, and of contAdolescence is typically fraught with problems, even under optimal conditions. And when chronic illness is added to the picture, medical and related social issues can complicate, and even disrupt, the course of development. The first text g
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, strained relationships, and difficulty in navigating new social roles. When individuals enter this developmental stage with a chronic illness, it can be especially trying. Despite how difficult this can be, little research has critically examined optimal, evidence-based ways of treating adolescent
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Introduction,uired by the German Egyptologist, Georg M. Ebers (1837–1898), and therefore called the ‘Ebers Papyrus’(Leake, 1952), possibly represents the first known medical text describing diabetes and its treatment (Figure 1.1). The ‘Ebers Papyrus’, a teaching text, was written about 1500 BC during the 18th Dy
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