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Titlebook: Human Chromosomes; Orlando J. Miller,Eeva Therman Textbook 2001Latest edition Springer Science+Business Media, LLC, part of Springer Natur

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书目名称Human Chromosomes
编辑Orlando J. Miller,Eeva Therman
视频video
图书封面Titlebook: Human Chromosomes;  Orlando J. Miller,Eeva Therman Textbook 2001Latest edition Springer Science+Business Media, LLC, part of Springer Natur
描述This is the fourth edition of an acclaimed introductory textbook on the structure and function of human chromosomes. The explosion of information on human genetic diseases has meant that there is a greater need than ever for students, practising physicians, laboratory technicians, and researchers to have a concise, up-to-date summary of the normal and abnormal behavior of chromosomes. This book continues to fulfill that need, and is strengthened by the complete revision of material on the molecular genetics of chromosomes and chromosomal defects.
出版日期Textbook 2001Latest edition
关键词Activation; Chromosom; DNA; Termination; biology; genes; genetics; hybridization
版次4
doihttps://doi.org/10.1007/978-1-4613-0139-4
isbn_softcover978-0-387-95046-4
isbn_ebook978-1-4613-0139-4
copyrightSpringer Science+Business Media, LLC, part of Springer Nature 2001
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In Situ Hybridization,s used, hybridization to complementary nucleic acid sequences in the target preparation can be achieved in a reasonably short time. These properties of DNA are extremely important, because they make it possible to detect specific DNA sequences (such as genes) on a nitrocellulose filter (.) or in cyt
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Meiotic Abnormalities: Abnormal Numbers of Chromosomes,r pole, rarely, one may misdivide at the centromere, just as univalents might in the first meiotic division. Only a small segment of the XY bivalent forms a synaptonemal complex in which crossing over takes place (Fig. 17.2). Thus, the X and Y remain as univalents much more often than even the small
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Abnormal Phenotypes Due to Autosomal Aneuploidy or Polyploidy,rmal neutrophil projections in trisomy 13. The increasingly routine use of ultrasound sometimes identifies fetal abnormalities at a stage of pregnancy at which a rapid decision is needed if termination of pregnancy is an option. Interphase FISH with DNA probes for chromosomes 13, 18, 21, X, and Y pe
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Sex Determination and the Y Chromosome,le cells. A number of groups have used powerful fluorescence-activated flow sorting to isolate the fetal cells, but the cells’ rarity has limited the development of this approach for early prenatal diagnosis. However, it has been used to diagnose trisomy 21 (.).
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The X Chromosome, Dosage Compensation, and X Inactivation,n every individual (male or female) with two or more X chromosomes, the maximum number of Barr bodies is one less than the number of X chromosomes. That is, one X remains euchromatic and the additional ones are heterochromatic. The heterochromatic X chromosomes replicate later in S than the euchroma
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