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Titlebook: Human Chromosomes; Structure, Behavior, Eeva Therman,Millard Susman Textbook 19933rd edition Springer-Verlag New York, Inc. 1993 Chromosom.

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Causes of Chromosome Breakage,e resulting aberrations can be studied in the next metaphase. However, before this takes place, a series of mechanisms, many of them still unknown, have played a role in the process (Natarajan, 1984; Savage, 1990). The first event is a “lesion”, i.e., some sort of DNA damage, the nature of which dep
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Chromosome Arrangement in Interphase and in Differentiated Nuclei,Carl Rabl showed that chromosomes remain in the same polarized orientation through interphase that they had assumed in anaphase. This Rabl orientation, as it has been called, is often still visible in the following prophase (Fig. 14.1a, b; Heitz, 1933). Rabl also found that chromosomes in interphase
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Modifications of Mitosis,ses are not necessarily correlated, and their relationship can be changed in different ways (Oksala, 1954). As a rule, such modifications lead to a chromosome constitution differing from the basic complement of the individual (Fig. 15.1). Apart from multipolar mitoses, all other mitotic modification
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Chromosomal Differentiation of Cells,sually divide spontaneously. However, in many cases they can be induced to undergo mitosis. Plant cells renew their mitotic activity around a wound, or after application of plant growth substances (Therman, 1951; D’Amato, 1952; Tschermak-Woess, 1956). Similarly, a portion of the mouse liver can be r
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