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Titlebook: Human Apolipoprotein Mutants III; Diagnosis and Treatm Cesare R. Sirtori,Guido Franceschini,Bryan H. Brew Conference proceedings 1993 Sprin

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书目名称Human Apolipoprotein Mutants III
副标题Diagnosis and Treatm
编辑Cesare R. Sirtori,Guido Franceschini,Bryan H. Brew
视频video
丛书名称Nato ASI Subseries H:
图书封面Titlebook: Human Apolipoprotein Mutants III; Diagnosis and Treatm Cesare R. Sirtori,Guido Franceschini,Bryan H. Brew Conference proceedings 1993 Sprin
描述Hopes to develop apolipoproteins for diagnostic or, evenbetter, therapeuticpurposes are growing. Areas of use mayrange from arterial disease to AIDS, fertilization programs,neurological or inflammatory disorders, and the like.However, these young members of the large family ofcirculating proteins still deserve careful study, both interms of structural and functional properties and of theirpathological changes. In addition, related molecules, inparticular belonging to the family of enzymes, such aslipases and acyltransferases, offer exciting insight intothemechanisms of regulation of lipid transport andexchange.Described hereis the use of apolipoproteins and enzymes inthe diagnosis of coronary andcerebrovascular disease.Structural and functional changes of apolipoproteins arerelated to lipid transport and binding to differentreceptors. Further, the development of apolipoprotein drugsand their possible clinical use for vascular and nonvascular disease is discussed and finally an overview onlipoprotein transformationprocesses, expression systems andnatural mutants is provided.
出版日期Conference proceedings 1993
关键词AIDS; Apolipoproteine; Arteriosklerose; Atherosklerose; Cardiology; Kardiologie; Koronarkrankheit; Lipid; ap
版次1
doihttps://doi.org/10.1007/978-3-642-84634-2
isbn_softcover978-3-642-84636-6
isbn_ebook978-3-642-84634-2Series ISSN 1010-8793
issn_series 1010-8793
copyrightSpringer-Verlag Berlin Heidelberg 1993
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Characterization of Lipoprotein Particles Containing Apolipoprotein A-IVHuman apolipoprotein A-IV (apo A-IV) is a 46,000 KD protein which is synthesized predominantly in the small intestine (Green et al., 1979 and 1980).
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978-3-642-84636-6Springer-Verlag Berlin Heidelberg 1993
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Human Apolipoprotein Mutants III978-3-642-84634-2Series ISSN 1010-8793
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Apolipoproteins as “Drugs”: Current Statusids and other chemicals, water soluble and in some cases presenting with a dominant positive or negative charge. In addition, some apolipoproteins can interact with cell receptors, either regulating cholesterol biosynthesis, or possibly cholesterol removal.
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