书目名称 | Human Apolipoprotein Mutants III | 副标题 | Diagnosis and Treatm | 编辑 | Cesare R. Sirtori,Guido Franceschini,Bryan H. Brew | 视频video | | 丛书名称 | Nato ASI Subseries H: | 图书封面 |  | 描述 | Hopes to develop apolipoproteins for diagnostic or, evenbetter, therapeuticpurposes are growing. Areas of use mayrange from arterial disease to AIDS, fertilization programs,neurological or inflammatory disorders, and the like.However, these young members of the large family ofcirculating proteins still deserve careful study, both interms of structural and functional properties and of theirpathological changes. In addition, related molecules, inparticular belonging to the family of enzymes, such aslipases and acyltransferases, offer exciting insight intothemechanisms of regulation of lipid transport andexchange.Described hereis the use of apolipoproteins and enzymes inthe diagnosis of coronary andcerebrovascular disease.Structural and functional changes of apolipoproteins arerelated to lipid transport and binding to differentreceptors. Further, the development of apolipoprotein drugsand their possible clinical use for vascular and nonvascular disease is discussed and finally an overview onlipoprotein transformationprocesses, expression systems andnatural mutants is provided. | 出版日期 | Conference proceedings 1993 | 关键词 | AIDS; Apolipoproteine; Arteriosklerose; Atherosklerose; Cardiology; Kardiologie; Koronarkrankheit; Lipid; ap | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-84634-2 | isbn_softcover | 978-3-642-84636-6 | isbn_ebook | 978-3-642-84634-2Series ISSN 1010-8793 | issn_series | 1010-8793 | copyright | Springer-Verlag Berlin Heidelberg 1993 |
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