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Titlebook: Human Achondroplasia; A Multidisciplinary Benedetto Nicoletti,Steven E. Kopits,Shona C. Dryb Book 1988 Plenum Press, New York 1988 Embryo.

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Gene Expression in the Early Mouse Embryo and Cultured Cellsn processes are programmed and coordinated during mammalian development. To this end, it has been important to isolate and characterize cell- and tissue-specific markers, genes and their products, which are expressed in early mouse embryogenesis. Indeed, a number of such markers have been identified
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Growth Plate Cartilage Studies in Achondroplasiahough its pathogenesis is thought to involve defective endochondral ossification, the specific way in which this occurs is not known. Previous studies of the growth plate in achondroplasia have suggested that the architecture of the growth plate may be mildly abnormal and that there may be abnormali
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Achondroplastic Mice: Morphological Investigations of Epiphyseal Cartilage and Bonevels of somatotropic hormone (6) and with skeletal abnormalities very similar to those which characterize human achondroplasia. Consequently, the cn/cn mice represent a useful model for studying human achondroplasia.
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GH Therapy in Two Patients with Osteochondrodysplasiaed cause and when this cause is specifically correctable. Hypopituitarism and coeliac disease are typical examples of this situation; in fact, growth hormone and a gluten-free diet, respectively, may achieve spectacular results. Therefore, no specific therapy is available nowadays for the great majo
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Achondroplastic Mice: Morphological Investigations of Epiphyseal Cartilage and Bonevels of somatotropic hormone (6) and with skeletal abnormalities very similar to those which characterize human achondroplasia. Consequently, the cn/cn mice represent a useful model for studying human achondroplasia.
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The Natural History of AchondroplasiaAchondroplasia is an important model for defining how to describe the natural history of a disorder, as well as how to use that information to judge various therapies and to prevent serious complications in the condition.
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Premutation in AchondroplasiaThe genetic characteristics of achondroplasia can be summarized as follows:
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