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Titlebook: Host Defenses to Intracellular Pathogens; Proceedings of a con Toby K. Eisenstein,Paul Actor,Herman Friedman Conference proceedings 1983 Th

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Mediator Interactions Regulating Macrophage Secretion of Interleukin 1 and Interferonisms appears, however, to be under regulatory control rather than static. Two mediators which appear to act in the process of macrophage differentiation and activation are interferon and colony-stimulating factor(s) (CSF). A substantial body of evidence indicates that interferon stimulates a variety
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Macrophage Oxygen-Dependent Killing of Intracellular Parasites: Toxoplasma and Leishmanias been known for some time that monocytes and macrophages play primary roles in the efferent limb of the cellular response to such infections (1–9). The mechanisms by which these phagocytes exert antimicrobial activity, however, have been largely unexplored. During the past several years, work in th
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Immunologic Lesions During , Infection. To investigate this, we have initiated studies of the responses in mice to various antigens during . infection. Experiments reported here indicate that different responses to thymic-independent (TI) and thymic-dependent (TD) antigenic challenges are seen which are consistent with an immunologic le
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Host Response to Infection with Mycobacterium Bovis (BCG) in Mice: Genetic Study of Natural Resistan response of outbred and inbred mice to infection with mycobacteria such as . and . have been noted for many years (2,3). We have recently reported that clear segregation of resistance and susceptibility to . (BCG), exists among mice of inbred strains infected with a single intravenous dose of this
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Cell Mediated Lysis of Lymphocytes Expressing Bacterial Antigensens. However, the T. is activated to kill only after collaboration with a second sub-population, the helper T cell (T.), which responds proliferatively to HLA-D antigens (1). We have asked whether purified protein derivative (PPD) and soluble Candida antigens (CAN) can substitute for foreign HLA-D i
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Improvement of Abnormal Lymphocyte Responses in “Atypical” Mycobacteriosis with Indomethacine improvement has been made in the treatment of diseases caused by nontuberculous mycobacteria. Depending on the type of hospital and population served by the hospital, the incidence of “atypical” mycobacteria may be as high as 30% of all mycobacterial infections (1). Aside from the clinical importa
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