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Titlebook: Hormone-Related Malignant Tumors; Lutwin Beck,Ekkehard Grundmann,Hans-Dietrich Röher Conference proceedings 1990 Springer-Verlag Berlin He

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书目名称Hormone-Related Malignant Tumors
编辑Lutwin Beck,Ekkehard Grundmann,Hans-Dietrich Röher
视频video
丛书名称Recent Results in Cancer Research
图书封面Titlebook: Hormone-Related Malignant Tumors;  Lutwin Beck,Ekkehard Grundmann,Hans-Dietrich Röher Conference proceedings 1990 Springer-Verlag Berlin He
描述The growth and function of many tissues are influenced by hormones. Therefore it is quite understandable that hormones play a role in the development and treatment of malignant tumors. Numerous publications address this topic; however, the results of many studies are controversial and have not been unequivocally accepted. For nearly 50 years the carcinogenic effect of steroid hormones has been under debate, and their therapeutic value a matter of discussion for equally as long. The present volume concentrates on substantiated data first obtained from the study of tumors developing from hormone­ regulated or hormone-producing tissue, e.g., the thyroid, adrenal glands, prostate, and the female genital tract. Through a joint approach from the field of molecular biology, biochemistry, and histopathology, advances in the management of these tumors have been elaborated. Another exciting example is the endo­ nuclear diagnosis of adrenal tumors. Antihormones, i.e. antian­ drogens or GnRH analogues have proved to be important indeed since they exhibit a destructive effect on prostate carcinomas and breast cancer. Further improvements can be expected in the localization of hormones in tumor
出版日期Conference proceedings 1990
关键词breast cancer; cancer; carcinoma; cell; endocrinology; growth; gynecology; histopathology; hormone; hormones;
版次1
doihttps://doi.org/10.1007/978-3-642-83816-3
isbn_softcover978-3-642-83818-7
isbn_ebook978-3-642-83816-3Series ISSN 0080-0015 Series E-ISSN 2197-6767
issn_series 0080-0015
copyrightSpringer-Verlag Berlin Heidelberg 1990
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New Developments in Biological Markers in Prostate Cancerins have enabled us to understand the potential and the problems associated with the use of these markers in clinical medicine. A review of biological markers in the prostate published previously by me (Pontes 1983) gave an extensive analysis of the value of specific and nonspecific markers in prostate cancer.
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Morphology and Functional Activity of Gastroenteropancreatic Neuroendocrine Tumourso define the nature of the cells. The tumours originating from these cells are rare, but by reproducing many of the morphological and functional features of their cell(s) of origin they reveal a distinct morphology and may give rise to a number of well-defined syndromes.
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Contributions of Nuclear Endocrinology to the Diagnosis of Adrenal Tumors7; Thrall et al. 1978; McEwan et al. 1985). A fundamental principle is that localizing procedures should be performed only when clinical suspicion has led to the performance of appropriate biochemical testing, the results of which support the diagnosis of an endocrine hypersecretory state.
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Antiandrogenic Substances in the Management of Prostatic Cancerfect of exogenous androgens in castrated animals. Antiandrogens probably exert their action at the target cell level by competing with androgens for receptor binding sites and by inhibiting the translocation of the hormone receptor complex into the nucleus (Neri 1977; Brinkmann et al. 1983).
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Endocrine Aspects of Medullary Thyroid Carcinomaportant clinical feature of MTC is its familial occurrence with an autosomal dominant pattern, its multifocal development of C cell hyperplasia prior to malignant transformation, and its association with other endocrine tumors (e.g., bilateral pheochromocytoma).
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Multiple Endocrine Neoplasia Type IIc changes in the pituitary gland, pancreatic islet cells, and parathyroid glands in virtually 100% of patients affected with MEN I even though many of the patients had no clinical or laboratory evidence of disease prior to death.
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