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Titlebook: Hormone Therapy and Castration Resistance of Prostate Cancer; Yoichi Arai,Osamu Ogawa Book 2018 Springer Nature Singapore Pte Ltd. 2018 An

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书目名称Hormone Therapy and Castration Resistance of Prostate Cancer
编辑Yoichi Arai,Osamu Ogawa
视频video
概述Elucidates the current status of hormone therapy for prostate cancer.Clarifies the differences between the evidence from Japan and that from Western countries on hormone therapy for prostate cancer.Br
图书封面Titlebook: Hormone Therapy and Castration Resistance of Prostate Cancer;  Yoichi Arai,Osamu Ogawa Book 2018 Springer Nature Singapore Pte Ltd. 2018 An
描述.This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged...During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnicvariation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspective
出版日期Book 2018
关键词Androgen deprivation therapy; Antiandrogen; Testosterone; Prostatectomy; Steroid therapy
版次1
doihttps://doi.org/10.1007/978-981-10-7013-6
isbn_softcover978-981-13-3906-6
isbn_ebook978-981-10-7013-6
copyrightSpringer Nature Singapore Pte Ltd. 2018
The information of publication is updating

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Bone Scan Index as a Biomarker of Bone Metastasis,ENAVI in Japan), and its advantages and disadvantages. The BSI could serve as a reliable marker of disease progression and treatment effects as well as a prognostic indicator. The index can also reflect the effects of new drugs and internal radiation therapy on bone metastasis and help in its management.
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Introduction,e situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy will finally form castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen.
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Patient-Derived Xenografts for Research on Hormonal Therapy of Prostate Cancer,t the molecular diversity of human prostate cancer. Herein, we will introduce representative prostate cancer PDX models, including our established models, and discuss potential usefulness together with future perspectives.
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Controversies on Combined Androgen Blockade for Prostate Cancer,inical trials to examine superiority of complete androgen blockade using adrenal androgen synthesis inhibitor or more powerful new antiandrogen instead of CAB as an initial treatment is ongoing for advanced prostate cancer.
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Adrenal Androgen in Prostate Cancer,after ADT that serves as the substrate for the production of more active androgens by steroidal metabolism enzymes. Production of active androgens participates in cancer proliferation to become castration-resistant Pca (CRPC).
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