Titlebook: Hormesis; A Revolution in Biol Mark P.‘Mattson,Edward J. Calabrese Book 2010 Humana Press 2010 aging.assessment.biology.cardiovascular dise

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The Fundamental Role of Hormesis in Evolution,, activate hormetic responses and examples of the genes and cellular and molecular pathways that mediate such adaptive stress responses are provided to illustrate how hormesis mediates natural selection.

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Transcriptional Mediators of Cellular Hormesis,nt stressors elicit unique signature responses, the comparison of prototypical hormetic inducers has highlighted the role played by a few transcription factor families. The periodic pulsatile activation of Nrf2, NF-κB, HSF, and FOXO has been found to be essential to obtaining the beneficial effects

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Couch Potato: The Antithesis of Hormesis,ysiological consequences of being a “couch potato.” Exercise and dietary energy restriction improve the functional efficiency of the heart and gut through a hormetic mechanism that involves increased activity of the parasympathetic component of the autonomic nervous system. As a consequence, heart r

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Book 2010at elucidate the molecular and cellular underpinnings of the biphasic dose response/hormesis. The implications of the tapping of cellular systems that underlie hormesis for the discovery and optimization of new drugs and dietary formulations are described. ..From environmental protection policy to m

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