书目名称 | Homology Modeling |
副标题 | Methods and Protocol |
编辑 | Andrew J. W. Orry,Ruben Abagyan |
视频video | |
概述 | Describes homology modeling steps from first principles.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplemen |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an .in silico. method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. .In, Homology Modelling: Methods and Protocols. experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful .Methods in Molecular Biology.™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.. .Thorough and intuitive, .Homology Modelling: Methods and Protocols. guides scientists in the available homology modeling methods.. . |
出版日期 | Book 2012 |
关键词 | Homology modeling; NMR structure; X-ray; in silico method; ligand-binding pocket; macromolecular assembli |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-61779-588-6 |
isbn_softcover | 978-1-4939-5880-1 |
isbn_ebook | 978-1-61779-588-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media,LLC 2012 |